Methylcobalamin, also known as Vitamin B12, is an important vitamin needed for the brain, nerves, and production of red blood cells in the body. It is used to treat not only vitamin B12 deficiency, but also other conditions, such as pernicious anemia and diabetes. It also helps increase metabolic energy and improve mood regulation. Some clinical trials are also testing its use in people with dementia as well.

Methylcobalamin is made both in the body and created within a laboratory for supplemental purposes. Most vitamin B12 supplements contain cyanocobalamin, which is another form of B12. However, in order for the B12 to be utilized in the body, the liver must detoxify the cyanocobalamin and attach it to a methyl group to form methylcobalamin, the biologically active and tissue-ready form. Research shows that methylcobalamin is more efficiently used and retained in the body than cyanocobalamin. Methylcobalamin can also be found in foods, such as clams, mollusks, liver, fish, lamb, veal, beef, and dairy products.

Biotin, also known as B7, is a water-soluble vitamin found in foods such as eggs, milk, and bananas. Biotin is involved in a wide range of metabolic processes primarily related to the utilization of fats, carbohydrates, and amino acids. It also influences cell growth and may help in maintaining blood sugar levels. Biotin is commonly supplemented for multiple conditions, such as hair loss, brittle nails, and nerve damage. Biotin is also thought to reduce inflammation, improve cognitive function, and increase HDL (good) cholesterol and decrease LDL (bad) cholesterol. It is rare to be deficient in biotin since only a small amount is needed to function properly. However, it is possible. Unlike other vitamin deficiency screenings, there isn’t a good laboratory test for detecting low biotin levels. Therefore, biotin deficiency is best identified by symptoms. These symptoms include thinning hair, a red, scaly rash around the nose, eyes, and mouth, depression, tiredness, hallucinations, and tingling of the arms and legs.

L-Glutathione, or simply glutathione, is a powerful antioxidant made of amino acids. Combined together, amino acids make up the proteins within the body. Unlike most antioxidants, glutathione can be made within the liver. This helps in the process of fat metabolism. Glutathione has many functions within the body. Some of these include supporting immune function, forming sperm cells, fighting free radicals, helping with certain enzyme functions, and making DNA. Glutathione is not only created naturally by the liver, but it is also found in fruits, vegetables, and meats. Glutathione can be given orally, intravenously (IV), intramuscularly, and as an inhalant. Supplementally, glutathione can be taken in the treatment and prevention of cataracts, glaucoma, aging, alcoholism, cancer, heart disease, liver disease, lung disease, Alzheimer’s disease, Parkinson’s disease, osteoarthritis, diseases that breakdown the body’s immune system, and many more.

Vitamin D is crucial to the building and maintenance of healthy bones and teeth. The recommended form of vitamin D is vitamin D3, known also as cholecalciferol. Calcium, the primary component of bone, is only properly absorbed by your body when vitamin D is present. Vitamin D is created within the body when direct sunlight converts a chemical in your skin into an active form of the vitamin. There are not many foods that contain vitamin D, but you can find it in fortified milk, fortified cereals, and fatty fish, like salmon, mackerel, and sardines. Unfortunately, most people do not get the necessary amount of vitamin D. Therefore, supplementation is needed. Vitamin D3 is the perfect supplement as it is the natural form of vitamin D that your body makes from sunlight.

Roles of vitamin D within the body, as stated by Medical News Today, include:

• Support of the immune system, brain, and nervous system
• Regulation of insulin levels, aiding in diabetes management
• Support of lung function and cardiovascular health
• Influence the expression of genes involved in cancer development

As previously stated, most people do not get the proper amount of vitamin D. There are many different factors that affect the amount of vitamin D that your skin produces. These factors include the time of day, season, latitude, skin pigmentation, location, and lifestyle. Someone living in a state, such as Florida, would produce more vitamin D compared to someone living in a state with less sunshine. It is said that sunscreen, while important, can decrease vitamin D production because it blocks the UVB rays needed.

NAD and NAD+ occur naturally in the body. They play a major role in
the chemical process of generating energy. NAD+ is probably the most important co-factor for improving mitochondrial function. Mitochondria are intracellular organelles (a.k.a. “energy powerhouses”) where micronutrients are converted to energy-rich ATP molecules for the cell. NAD helps the liver break down fats that are essential to provide energy for the body. Boosting NAD+ may help manage a wide spectrum of diseases, ranging from diabetes to cancer. When NAD is given intravenous, some research has shown it can improve: